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Top Cast
Ellen Burstyn
Sara Goldfarb
Jared Leto
Harry Goldfarb
Jennifer Connelly
Marion Silver
Marlon Wayans
Tyrone C. Love
Christopher McDonald
Tappy Tibbons
Louise Lasser
Ada
Marcia Jean Kurtz
Rae
Janet Sarno
Mrs. Pearlman
Suzanne Shepherd
Mrs. Scarlini
Joanne Gordon
Mrs. Ovadia
Charlotte Aronofsky
Mrs. Miles
Mark Margolis
Mr. Rabinowitz
Michael Kaycheck
Donut Cop
Jack O'Connell
Corn Dog Stand Boss
Chas Mastin
Lyle Russel
Ajay Naidu
Mailman
Sean Gullette
Arnold the Shrink
Samia Shoaib
Nurse Mall
Peter Maloney
Dr. Pill
Abraham Abraham
King Neptune
Aliya Campbell
Alice
Te'ron A. O'Neal
Young Tyrone
Denise Dowse
Tyrone's Mother
Bryan Chattoo
Brody
Eddie De Harp
Brody's Henchman Victor
Scott Franklin
Jailer (voice)
Peter Cheyenne
Sal the Geep
Brian Costello
First AD
Abraham Aronofsky
Newspaper Man on Train
James Chinlund
Space Oddity
Olga Merediz
Malin & Block Secretary
Allison Furman
Malin & Block Office Woman
Robert Dylan Cohen
Paramedic Greenhill
Ben Shenkman
Dr. Spencer
Keith David
Big Tim
Dylan Baker
Southern Doctor
Shaun O'Hagan
Ward Attendant Seto
Leland Gantt
Ward Attendant Penn
Bill Buell
Court Doctor
Jimmie Ray Weeks
Prison Guard
Gregg Bello
E.R. Doctor
Henry Stram
ECT Technician
Heather Litteer
Big Tim Party Girl
Jenny Decker
Big Tim Party Girl
Ami Goodheart
Big Tim Party Girl
Nina Zavarin
Big Tim Party Girl
Stanley B. Herman
Uncle Hank
Scott Bader
Party Animal
Jim Centofanti
Party Animal
Scott Chait
Party Animal
Daniel Clarin
Party Animal
Ben Cohen
Party Animal
Eric Cohen
Party Animal
Brett Feinstein
Party Animal
Ricky Fier
Party Animal
John Getz
Party Animal
Andrew Kessler
Party Animal
Ross Lombardo
Party Animal
Carter Mansbach
Party Animal
Scott Miller
Party Animal
Todd Miller
Party Animal
Joshua Pollack
Party Animal
Craig Rallo
Party Animal
Geordan Reisner
Party Animal
Keith Scandore
Party Animal
David Seltzer
Party Animal
Chris Varvaro
Party Animal
Ricardo Viñas
Party Animal
Chad Weiner
Party Animal
Jesse Weissberger
Party Animal
Greg Weissman
Party Animal
Hubert Selby Jr.
Laughing Guard
Lianna Pai
Angelic Nurse
Darren Aronofsky
Visitor (uncredited)