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Top Cast
Russell Brand
E.B (voice)
James Marsden
Fred
Kaley Cuoco
Samantha O'Hare
Hank Azaria
Carlos / Phil (voice)
Elizabeth Perkins
Bonnie O'Hare
Gary Cole
Henry O'Hare
Hugh Laurie
E.B.'s Dad (voice)
David Hasselhoff
David Hasselhoff
Chelsea Handler
Mrs. Beck
Dustin Ybarra
Cody
Tiffany Espensen
Alex O'Hare
Jimmy Carter
Blind Boys of Alabama
Veronica Alicino
Waitress
Coleton Ray
Young Fred
Mark Riccardi
Security Guard
Greg Lewis
Performer
Hugh Hefner
Voice at Playboy Mansion (voice)
Rick Pasqualone
Utility Voice
Django Marsh
Young E.B. (voice)
Robbie Tucker
Kid#1 (uncredited)
Crystal the Monkey
Monkey (uncredited)