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Top Cast
Will Ferrell
Sherlock Holmes
John C. Reilly
Dr. John Watson
Rebecca Hall
Dr. Grace Hart
Kelly Macdonald
Mrs. Martha Hudson
Rob Brydon
Inspector Lestrade
Lauren Lapkus
Millie
Pam Ferris
Queen Victoria
Ralph Fiennes
Prof. James Moriarty / Jacob Musgrave
Adam Scherr
Brawn
Kieran O'Brien
PC Smalls
Noah Jupe
Doxy
Bella Ramsey
Flotsam
Colby Mulgrew
Haybag
Scarlet Grace
Pickle
Billy Jenkins
Mud Fog
Michael Culkin
The Judge
Wolf Roth
Sigmund Freud
Jana Pérez
Lestrade's Wife
Nathan Osgood
Mark Twain
David Shackleton
Albert Einstein
Paul Cassidy
Charlie Chaplin
Bronson Webb
Jonathan Nightingale
Jamie-Rose Monk
Mrs. Nightingale
Jason Thorpe
Butler
Robert Cawsey
Waiter
Stanley Eldridge
Waiter
Oliver Maltman
Telegraph Operator
David Stoller
Hudson's Guard
Jack Riley
Newschild
Lilly Aspell
Newschild
Ethan Rouse
Newschild
Ellie Rose Eames
Newschild
Jamie Baughan
Titanic Ship Officer Liaison
Helen Duff
Titanic Guest
Jess Liaudin
Hangman
Wesley Kent-Hargreaves
Weird Child Companion
Daniel Fearn
Drooling Man Companion
Darren Lake
Disorientated Man Companion
Martin Bishop
Priest
Gerard Monaco
Titanic Ship Officer
Ben Lee
Houdini
Michael Buffer
Fight Fan #1
Bruce Buffer
Fight Fan #2
Russell Wilcox
Announcer
Billy Zane
Billy Zane
Hector Bateman-Harden
Young Sherlock Holmes
Codie-Lei Eastick
Young Watson
Laura Stevely
Sherlock's Mother
Layla Rose Boyce
Nicotine Stains / Nancy
Sadie Newman
Jane
Harry Baxendale
Seamus
Ella Bright
Bridgette
Kenneth Hadley
Headmaster
Paul Bigley
Teacher #1
Sue Maund
Teacher #2
Tommy Gene Surridge
Inky Hands
Paddy Holland
Tough Kid
Henrihs Ahmadejevs
Drunk (uncredited)
Deepak Anand
Nobleman (uncredited)
Lindy Barrett
School Girl (uncredited)
Martin Bassindale
One Man Band (uncredited)
Sara Beasley
Mrs. Frobisher (uncredited)
Steve Coogan
Gustav (uncredited)
Willem Dalby
Newsie Man (uncredited)
Matthew Di Liello
Telly-Phone Assistant (uncredited)
Shawn Dixon
Upper Class Gentleman #1 (uncredited)
Paul T.T. Easter
John (uncredited)
James Eeles
Manager Mr. Petrucka (uncredited)
Karl Farrer
Russian Merchant (uncredited)
David Handley
Executioner (uncredited)
Phil Hodges
Mr. Algernon Barkworth (uncredited)
John Kinory
Instructing Solicitor (uncredited)
Craig Thomas Lambert
Yeoman of the guard (uncredited)
Hugh Laurie
Mycroft Holmes (uncredited)
Benjamin Lok
Courtroom Person 3 (uncredited)
Jordan Long
Herbert (uncredited)
Joseph Macnab
Fitness Instructor (uncredited)
Jorge Leon Martinez
British Soldier (uncredited)
Martyn Mayger
Buckingham Palace Guest (uncredited)
Hugh O'Brien
Garden Party Guest (uncredited)
Amelia O'Loughlin
White Star-Line Girl (uncredited)
Anthony Richard Rowe
Victorian Gentleman (uncredited)
Pete Freerunner Simpson
Police Officer (uncredited)
Sonnyboy Skelton
Doxy's Dad (uncredited)
Mick Slaney
Docker (uncredited)
Samantha Sharon Watson
Elizabeth - Lady of the Night (uncredited)
Lochlan White
Newsie Kid - Timmy (uncredited)
Riley White
Newsie Kid - Jimmy (uncredited)